Surrogate Endpoint - Criticism

Criticism

There have been a number of instances when studies using surrogate markers have been used to show benefit from a particular treatment, but later, a repeat study looking at endpoints has not shown a benefit, or even a harm.

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Famous quotes containing the word criticism:

    ...I wasn’t at all prepared for the avalanche of criticism that overwhelmed me. You would have thought I had murdered someone, and perhaps I had, but only to give her successor a chance to live. It was a very sad business indeed to be made to feel that my success depended solely, or at least in large part, on a head of hair.
    Mary Pickford (1893–1979)

    Homoeopathy is insignificant as an art of healing, but of great value as criticism on the hygeia or medical practice of the time.
    Ralph Waldo Emerson (1803–1882)

    As far as criticism is concerned, we don’t resent that unless it is absolutely biased, as it is in most cases.
    John Vorster (1915–1983)