Surrogate Endpoint - Criticism

Criticism

There have been a number of instances when studies using surrogate markers have been used to show benefit from a particular treatment, but later, a repeat study looking at endpoints has not shown a benefit, or even a harm.

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Famous quotes containing the word criticism:

    Unless criticism refuses to take itself quite so seriously or at least to permit its readers not to, it will inevitably continue to reflect the finicky canons of the genteel tradition and the depressing pieties of the Culture Religion of Modernism.
    Leslie Fiedler (b. 1917)

    In criticism I will be bold, and as sternly, absolutely just with friend and foe. From this purpose nothing shall turn me.
    Edgar Allan Poe (1809–1845)

    Homoeopathy is insignificant as an art of healing, but of great value as criticism on the hygeia or medical practice of the time.
    Ralph Waldo Emerson (1803–1882)