Human
Three forms of superoxide dismutase are present in humans, in all other mammals, and most chordates. SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. The first is a dimer (consists of two units), whereas the others are tetramers (four subunits). SOD1 and SOD3 contain copper and zinc, whereas SOD2, the mitochondrial enzyme, has manganese in its reactive centre. The genes are located on chromosomes 21, 6, and 4, respectively (21q22.1, 6q25.3 and 4p15.3-p15.1).
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Read more about this topic: Superoxide Dismutase, Types
Famous quotes containing the word human:
“He, who, in view of its inconsistencies, says of human nature the same that, in view of its contrasts, is said of the divine nature, that it is past finding out, thereby evinces a better appreciation of it than he who, by always representing it in a clear light, leaves it to be inferred that he clearly knows all about it.”
—Herman Melville (1819–1891)
“There’s nothing that makes you so aware of the improvisation of human existence as a song unfinished. Or an old address book.”
—Carson McCullers (1917–1967)
“The household is a school of power. There, within the door, learn the tragi-comedy of human life.”
—Ralph Waldo Emerson (1803–1882)