Human
Three forms of superoxide dismutase are present in humans, in all other mammals, and most chordates. SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. The first is a dimer (consists of two units), whereas the others are tetramers (four subunits). SOD1 and SOD3 contain copper and zinc, whereas SOD2, the mitochondrial enzyme, has manganese in its reactive centre. The genes are located on chromosomes 21, 6, and 4, respectively (21q22.1, 6q25.3 and 4p15.3-p15.1).
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Read more about this topic: Superoxide Dismutase, Types
Famous quotes containing the word human:
“There should be more sincerity and heart in human relations, more silence and simplicity in our interactions. Be rude when youre angry, laugh when something is funny, and answer when youre asked.”
—Anton Pavlovich Chekhov (18601904)
“From this fat dungeon I could rise to skin
And human title, putting pig within.”
—Thom Gunn (b. 1929)
“How rare to be born a human being!
Wash him off with cedar-bark and milkweed
send the damned doctors home.
Baby, baby, noble baby,
Noble-hearted baby”
—Gary Snyder (b. 1930)