Strychnine - Human Toxicity

Human Toxicity

Strychnine is very toxic to humans and many other animals; the symptoms of poisoning are generally the same as in other animals, because the mechanism of action is apparently similar across different species. The toxicity of strychnine in humans has not been widely studied, for obvious reasons. Most of the information known today comes from real-life cases of strychnine poisoning, both unintentional and deliberate. The LD50-values estimated from different cases of strychnine poisoning are listed below in table 2.

The LD50 values for strychnine in humans
Route LD50 (mg)
Human Oral 100-120
Human Oral 30-60
Human (child) Oral 15
Human (adult) Oral 50-100
Human (adult) Oral 30-100
Human (adult) Oral 30
Human Intravenously 5-10 (approximate)

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