Strongyloides Stercoralis - Chemoattractant

Chemoattractant

This parasite depends on chemical cues to find a potential host. It uses sensor neurons of class AFD to identify cues excreted by the host.S. stercoralis is attracted to nonspecific attractants of warmth, carbon dioxide, and sodium chloride. Urocanic acid, a component of skin secretions in mammals, is a major chemoattractant. Larvae of S. stercoralis are strongly attracted to this compound. This compound can be suppressed by metal ions, suggesting a possible strategy for preventing infection.

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