Skin Disease
An inability to correctly maintain the skin barrier function due to the dysregulation of epidermal components can lead to skin disorders. For example, a failure to modulate the activity of kallikreins via the disruption of the protease inhibitor LEKTI causes the debilitating disorder Netherton syndrome.
Read more about this topic: Stratum Corneum
Famous quotes containing the words skin and/or disease:
“The hand I burned and whose skin is shriveled like that of a mummys is less sensitive than the other to cold or heat. My soul is the same; it passed through fire.”
—Gustave Flaubert (18211880)
“War is in truth a disease in which the juices that serve health and maintenance are used for the sole purpose of nourishing something foreign, something at odds with nature.”
—Johann Wolfgang Von Goethe (17491832)