Stiff Person Syndrome - Prognosis

Prognosis

Patients with Stiff-person syndrome usually respond well to muscle relaxants and their condition can stabilize after months to years of progression. Those with Stiff-limb syndrome have a poorer prognosis, as they do not respond well to medications. These patients often require a wheelchair.

Prognosis is variable and there is no reliable predictor of speed and severity of disease onset. Muscle tetany may lead to muscle rupture and broken bones, or problems swallowing and breathing in severe cases.

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