Stefani may refer to:
- Stefani, Boeotia, a settlement in Boeotia, Greece
- Stefani, Corinthia, a village in the municipal unit of Tenea
- Stefani, Preveza, a village in the municipality of Louros, Preveza regional unit, Greece
- Stefani, Trikala, a village in the municipality of Kalampaka, Trikala regional unit, Greece
- 4624 Stefani (1982 FV2), a main-belt asteroid
- People
- Alberto De Stefani (1879–1969), Italian politician
- Andrea Stefani, Albanian journalist
- Enrico Stefani, Italian architect and archaeologist
- Eric Stefani (born 1967), American musician and animator
- Graciela Stefani, Argentine screen and stage actress
- Gwen Stefani (born 1969), American pop, rock, R&B and ska singer
- Luca Stefani (born 1987), Italian long track speed skater
- Pier Luigi Stefani, Italian TV producer
- Simon Stefani, Albanian politician
- Stefano Stefani (born 1938), Venetist Italian politician
- Stefani Germanotta (born 1986), American pop singer, known professionally as Lady Gaga
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