Spontaneous Cerebrospinal Fluid Leak

Spontaneous Cerebrospinal Fluid Leak

Spontaneous cerebrospinal fluid leak syndrome (SCSFLS) is a medical condition in which the cerebrospinal fluid (CSF) held in and around a human brain and spinal cord leaks out of the surrounding protective sac, the dura, for no apparent reason. The dura, a tough, inflexible tissue, is the outermost of the three layers of the meninges, the system of meninges surrounding the brain and spinal cord. (The other two meningeal layers are the pia mater and the arachnoid mater).

A spontaneous cerebrospinal fluid leak is one of several types of cerebrospinal fluid leaks and occurs due to the presence of one or more holes in the dura. A spontaneous CSF leak, as opposed to traumatically caused CSF leaks, arises idiopathically. A loss of CSF greater than its rate of production leads to a decreased volume inside the skull known as intracranial hypotension. A CSF leak is most often characterized by a severe and disabling headache and a spectrum of various symptoms which occur as a result of intracerebral hemorrhage (ICH). These symptoms can include: dizziness, nausea, fatigue, a metallic taste in the mouth (indicative of a cranial leak), myoclonus, tinnitus, tingling in the limbs, and facial weakness amongst others. A CT scan can identify the site of a cerebrospinal fluid leakage. Once identified, the leak can often be repaired by an epidural blood patch, an injection of the patient's own blood at the site of the leak, fibrin glue injection or surgery.

SCSFLS afflicts 5 out of every 100,000 people. On average, the condition is developed at the age of 42, and women are twice as likely as men to develop the condition. Some people with SCSFLS chronically leak cerebrospinal fluid despite repeated attempts at patching, leading to long-term disability due to pain and nerve damage. SCSFLS was first described by German neurologist Georg Schaltenbrand in 1938 and by American physician Henry Woltman of the Mayo Clinic in the 1950s.

Read more about Spontaneous Cerebrospinal Fluid LeakClassification, Signs and Symptoms, Causes, Pathophysiology, Diagnosis, Prognosis, Epidemiology, History, Research and Experimental Treatments, See Also

Other articles related to "cerebrospinal, cerebrospinal fluid leak, leaks, spontaneous cerebrospinal fluid leak, leak":

Syrinx (medicine) - Description
... A syrinx results when a watery, protective substance known as cerebrospinal fluid, that normally flows around the spinal cord and brain, transporting nutrients and waste products ... A number of medical conditions can cause an obstruction in the normal flow of cerebrospinal fluid, redirecting it into the spinal cord itself ... Cerebrospinal fluid fills the syrinx ...
Ventriculitis - Treatment
... the symptoms and control the infection while the cerebrospinal fluid samples are analyzed ... of non-invasively allowing the drugs to enter the cerebrospinal fluid ... Should intracranial pressure reach unsafe levels, the patient may need to have cerebrospinal fluid drained ...
Hydrocephalus - Classification - Communicating
... hydrocephalus, is caused by impaired cerebrospinal fluid resorption in the absence of any CSF-flow obstruction between the ventricles and subarachnoid space ... located along the superior sagittal sinus and is the site of cerebrospinal fluid resorption back into the venous system ... enlarged cerebral ventricles, with only intermittently elevated cerebrospinal fluid pressure ...
Cerebrospinal Fluid Leak
... A cerebrospinal fluid leak (CSFL) is a medical condition when the cerebrospinal fluid of a person leaks out of the dura mater ... This can be caused by several reasons, including spontaneous cerebrospinal fluid leak, post-surgical lumbar puncture (iatrogenic), physical trauma, etc ... While high CSF pressure can make reclining unbearable, low CSF pressure due to a leak is often relieved somewhat by maintaining a supine position ...
Cerebrospinal Fluid Rhinorrhoea
... CSF rhinorrhoea refers to the drainage of cerebrospinal fluid through the nose ... Management includes watchful waiting - leaks often stop spontaneously if this does not occur then neurosurgical closure is necessary to prevent the spread of infection to the meninges ... in some patients, as the communication between the nasal cavity and the cerebrospinal fluid and CNS can result in bacterial infections of the CNS that can have catastrophic ...

Famous quotes containing the words leak, fluid and/or spontaneous:

    The office ... make[s] its incumbent a repair man behind a dyke. No sooner is one leak plugged than it is necessary to dash over and stop another that has broken out. There is no end to it.
    Herbert Hoover (1874–1964)

    It is more than likely that the brain itself is, in origin and development, only a sort of great clot of genital fluid held in suspense or reserved.... This hypothesis ... would explain the enormous content of the brain as a maker or presenter of images.
    Ezra Pound (1885–1972)

    What is saved in the cinema when it achieves art is a spontaneous continuity with all mankind. It is not an art of the princes or the bourgeoisie. It is popular and vagrant. In the sky of the cinema people learn what they might have been and discover what belongs to them apart from their single lives.
    John Berger (b. 1926)