Spindle Apparatus - Regulation of Spindle Assembly

Regulation of Spindle Assembly

Aurora A is required for proper spindle assembly and separation. There have been identified many proteins necessary for the mitotic spindle assembly. Lamin B is not an essential protein for spindle assembly. It is only a component of the spindle matrix helping microtubule assembly, since proper mitotic spindle can be formed without it.

Polo-like kinase, also known as PLK, especially PLK1 has important roles in the spindle maintenance by regulating microtubule dynamics.

Read more about this topic:  Spindle Apparatus

Famous quotes containing the words regulation of, regulation and/or assembly:

    Nothing can be more real, or concern us more, than our own sentiments of pleasure and uneasiness; and if these be favourable to virtue and unfavourable to vice, no more can be requisite to the regulation of our conduct and behavior.
    David Hume (1711–1776)

    Lots of white people think black people are stupid. They are stupid themselves for thinking so, but regulation will not make them smarter.
    Stephen Carter (b. 1954)

    That man is to be pitied who cannot enjoy social intercourse without eating and drinking. The lowest orders, it is true, cannot imagine a cheerful assembly without the attractions of the table, and this reflection alone should induce all who aim at intellectual culture to endeavor to avoid placing the choicest phases of social life on such a basis.
    Mrs. H. O. Ward (1824–1899)