Spaulding Turnpike

The Spaulding Turnpike is a toll road in New Hampshire, USA, running 33 miles (53 km) from Interstate 95 in Portsmouth northwest to Milton. The turnpike roughly parallels the Maine border, and in the mid-1990s New Hampshire Route 16 was re-signed onto the turnpike. There are two toll plazas on the turnpike, in Dover and Rochester.

The turnpike is part of the New Hampshire Turnpike System operated by the New Hampshire Department of Transportation Bureau of Turnpikes. It is a 4-lane divided highway from Portsmouth to Rochester. From exit 12 at NH Route 125 south of Rochester north to the highway's terminus in Milton it is a two-lane freeway, although it is currently being widened to four lanes through Rochester, between exits 11 and 16. Route 16 continues as an all-access highway north of Milton.

Exit 1, on the border between Portsmouth and Newington, was previously an at-grade crossing with traffic lights, most likely due to the proximity of the entrance to Pease Air Force Base. After the base's closure, it was converted into a diamond interchange.