Zoe Palaiologina (Greek: Ζωή Παλαιολογίνα), who later changed her name to Sophia Palaiologina (Russian: София Фоминична Палеолог; between 1440 and 1449 or c. 1455 – 7 April 1503), Grand Duchess of Moscow, was a niece of the last Byzantine emperor Constantine XI and second wife of Ivan III of Russia. She was also the grandmother of Ivan the Terrible.