Safety
See also: Fluoride poisoningThe lethal dose for a 70 kg (154 lb) human is estimated at 5–10 g. Sodium fluoride is classed as toxic by both inhalation (of dusts or aerosols) and ingestion. In high enough doses, it has been shown to affect the heart and circulatory system.
In the higher doses used to treat osteoporosis, plain sodium fluoride can cause pain in the legs and incomplete stress fractures when the doses are too high; it also irritates the stomach, sometimes so severely as to cause ulcers. Slow-release and enteric-coated versions of sodium fluoride do not have gastric side effects in any significant way, and have milder and less frequent complications in the bones. In the lower doses used for water fluoridation, the only clear adverse effect is dental fluorosis, which can alter the appearance of children's teeth during tooth development; this is mostly mild and is unlikely to represent any real effect on aesthetic appearance or on public health.
Read more about this topic: Sodium Fluoride
Famous quotes containing the word safety:
“The safety of the republic being the supreme law, and Texas having offered us the key to the safety of our country from all foreign intrigues and diplomacy, I say accept the key ... and bolt the door at once.”
—Andrew Jackson (1767–1845)
“He had a gentleman-like frankness in his behaviour, and as a great point of honour as a minister can have, especially a minister at the head of the treasury, where numberless sturdy and insatiable beggars of condition apply, who cannot all be gratified, nor all with safety be refused.”
—Philip Dormer Stanhope, 4th Earl Chesterfield (1694–1773)
“If we can find a principle to guide us in the handling of the child between nine and eighteen months, we can see that we need to allow enough opportunity for handling and investigation of objects to further intellectual development and just enough restriction required for family harmony and for the safety of the child.”
—Selma H. Fraiberg (20th century)