Types
The two most well known members of SGLT family are SGLT1 and SGLT2, which are members of the SLC5A gene family.
| Gene | Protein | Acronym | Tissue distribution in proximal tubule |
Na+:Glucose Co-transport ratio |
Contribution to glucose reabsorption (%) |
|---|---|---|---|---|---|
| SLC5A1 | Sodium/GLucose coTransporter 1 |
SGLT1 | S3 segment | 2:1 | 10 |
| SLC5A2 | Sodium/GLucose coTransporter 2 |
SGLT2 | predominately in the S1 and S2 segments |
1:1 | 90 |
Including SGLT1 and SGLT2, there are total seven members in the human protein family SLC5A, several of which may also be sodium-glucose transporters.
Read more about this topic: Sodium-glucose Transport Proteins
Famous quotes containing the word types:
“... there are two types of happiness and I have chosen that of the murderers. For I am happy. There was a time when I thought I had reached the limit of distress. Beyond that limit, there is a sterile and magnificent happiness.”
—Albert Camus (1913–1960)
“The American man is a very simple and cheap mechanism. The American woman I find a complicated and expensive one. Contrasts of feminine types are possible. I am not absolutely sure that there is more than one American man.”
—Henry Brooks Adams (1838–1918)
“If there is nothing new on the earth, still the traveler always has a resource in the skies. They are constantly turning a new page to view. The wind sets the types on this blue ground, and the inquiring may always read a new truth there.”
—Henry David Thoreau (1817–1862)