Types
The two most well known members of SGLT family are SGLT1 and SGLT2, which are members of the SLC5A gene family.
| Gene | Protein | Acronym | Tissue distribution in proximal tubule |
Na+:Glucose Co-transport ratio |
Contribution to glucose reabsorption (%) |
|---|---|---|---|---|---|
| SLC5A1 | Sodium/GLucose coTransporter 1 |
SGLT1 | S3 segment | 2:1 | 10 |
| SLC5A2 | Sodium/GLucose coTransporter 2 |
SGLT2 | predominately in the S1 and S2 segments |
1:1 | 90 |
Including SGLT1 and SGLT2, there are total seven members in the human protein family SLC5A, several of which may also be sodium-glucose transporters.
Read more about this topic: Sodium-glucose Transport Proteins
Famous quotes containing the word types:
“He’s one of those know-it-all types that, if you flatter the wig off him, he chatter like a goony bird at mating time.”
—Michael Blankfort. Lewis Milestone. Johnson (Reginald Gardner)
“The wider the range of possibilities we offer children, the more intense will be their motivations and the richer their experiences. We must widen the range of topics and goals, the types of situations we offer and their degree of structure, the kinds and combinations of resources and materials, and the possible interactions with things, peers, and adults.”
—Loris Malaguzzi (1920–1994)
“The rank and file have let their servants become their masters and dictators.... Provision should be made in all union constitutions for the recall of leaders. Big salaries should not be paid. Career hunters should be driven out, as well as leaders who use labor for political ends. These types are menaces to the advancement of labor.”
—Mother Jones (1830–1930)