SNP Genotyping - Other Post-amplification Methods Based On Physical Properties of DNA

Other Post-amplification Methods Based On Physical Properties of DNA

The characteristic DNA properties of melting temperature and single stranded conformation have been used in several applications to distinguish SNP alleles. These methods very often achieve high specificity but require highly optimized conditions to obtain the best possible results.

Read more about this topic:  SNP Genotyping

Famous quotes containing the words methods, based, physical, properties and/or dna:

    Commerce is unexpectedly confident and serene, alert, adventurous, and unwearied. It is very natural in its methods withal, far more so than many fantastic enterprises and sentimental experiments, and hence its singular success.
    Henry David Thoreau (1817–1862)

    Because it is not always easy for an adult to predict what inaccurate ideas a child may have, it can help to answer questions first with one of your own: “What do you think?” Once you find out what a child is really asking, you’ll be in a better position to give a helpful answer based on the facts.
    Joanna Cole (20th century)

    A separation situation is different for adults than it is for children. When we were very young children, a physical separation was interpreted as a violation of our inalienable rights....As we grew older, the withdrawal of love, whether that meant being misunderstood, mislabeled or slighted, became the separation situation we responded to.
    Roger Gould (20th century)

    A drop of water has the properties of the sea, but cannot exhibit a storm. There is beauty of a concert, as well as of a flute; strength of a host, as well as of a hero.
    Ralph Waldo Emerson (1803–1882)

    Here [in London, history] ... seemed the very fabric of things, as if the city were a single growth of stone and brick, uncounted strata of message and meaning, age upon age, generated over the centuries to the dictates of some now all-but-unreadable DNA of commerce and empire.
    William Gibson (b. 1948)