Other Post-amplification Methods Based On Physical Properties of DNA
The characteristic DNA properties of melting temperature and single stranded conformation have been used in several applications to distinguish SNP alleles. These methods very often achieve high specificity but require highly optimized conditions to obtain the best possible results.
Read more about this topic: SNP Genotyping
Famous quotes containing the words methods, based, physical, properties and/or dna:
“The reading public is intellectually adolescent at best, and it is obvious that what is called significant literature will only be sold to this public by exactly the same methods as are used to sell it toothpaste, cathartics and automobiles.”
—Raymond Chandler (18881959)
“Our children evaluate themselves based on the opinions we have of them. When we use harsh words, biting comments, and a sarcastic tone of voice, we plant the seeds of self-doubt in their developing minds.... Children who receive a steady diet of these types of messages end up feeling powerless, inadequate, and unimportant. They start to believe that they are bad, and that they can never do enough.”
—Stephanie Martson (20th century)
“For pain is perhaps but a violent pleasure? Who could determine the point where pleasure becomes pain, where pain is still a pleasure? Is not the utmost brightness of the ideal world soothing to us, while the lightest shadows of the physical world annoy?”
—HonorĂ© De Balzac (17991850)
“The reason why men enter into society, is the preservation of their property; and the end why they choose and authorize a legislative, is, that there may be laws made, and rules set, as guards and fences to the properties of all the members of the society: to limit the power, and moderate the dominion, of every part and member of the society.”
—John Locke (16321704)
“Here [in London, history] ... seemed the very fabric of things, as if the city were a single growth of stone and brick, uncounted strata of message and meaning, age upon age, generated over the centuries to the dictates of some now all-but-unreadable DNA of commerce and empire.”
—William Gibson (b. 1948)