Other Post-amplification Methods Based On Physical Properties of DNA
The characteristic DNA properties of melting temperature and single stranded conformation have been used in several applications to distinguish SNP alleles. These methods very often achieve high specificity but require highly optimized conditions to obtain the best possible results.
Read more about this topic: SNP Genotyping
Famous quotes containing the words methods, based, physical, properties and/or dna:
“A writer who writes, “I am alone” ... can be considered rather comical. It is comical for a man to recognize his solitude by addressing a reader and by using methods that prevent the individual from being alone. The word alone is just as general as the word bread. To pronounce it is to summon to oneself the presence of everything the word excludes.”
—Maurice Blanchot (b. 1907)
“The trouble with this country is that there are too many politicians who believe, with a conviction based on experience, that you can fool all of the people all of the time.”
—Franklin Pierce Adams (1881–1960)
“Dance is bigger than the physical body. ...When you extend your arm, it doesn’t stop at the end of your fingers, because you’re dancing bigger than that; you’re dancing spirit.”
—Judith Jamison (b. 1943)
“The reason why men enter into society, is the preservation of their property; and the end why they choose and authorize a legislative, is, that there may be laws made, and rules set, as guards and fences to the properties of all the members of the society: to limit the power, and moderate the dominion, of every part and member of the society.”
—John Locke (1632–1704)
“Here [in London, history] ... seemed the very fabric of things, as if the city were a single growth of stone and brick, uncounted strata of message and meaning, age upon age, generated over the centuries to the dictates of some now all-but-unreadable DNA of commerce and empire.”
—William Gibson (b. 1948)