Other Post-amplification Methods Based On Physical Properties of DNA
The characteristic DNA properties of melting temperature and single stranded conformation have been used in several applications to distinguish SNP alleles. These methods very often achieve high specificity but require highly optimized conditions to obtain the best possible results.
Read more about this topic: SNP Genotyping
Famous quotes containing the words methods, based, physical, properties and/or dna:
“If you want to know the taste of a pear, you must change the pear by eating it yourself.... If you want to know the theory and methods of revolution, you must take part in revolution. All genuine knowledge originates in direct experience.”
—Mao Zedong (1893–1976)
“Language makes it possible for a child to incorporate his parents’ verbal prohibitions, to make them part of himself....We don’t speak of a conscience yet in the child who is just acquiring language, but we can see very clearly how language plays an indispensable role in the formation of conscience. In fact, the moral achievement of man, the whole complex of factors that go into the organization of conscience is very largely based upon language.”
—Selma H. Fraiberg (20th century)
“There are two kinds of timidity—timidity of mind, and timidity of the nerves; physical timidity, and moral timidity. Each is independent of the other. The body may be frightened and quake while the mind remains calm and bold, and vice versë. This is the key to many eccentricities of conduct. When both kinds meet in the same man he will be good for nothing all his life.”
—Honoré De Balzac (1799–1850)
“The reason why men enter into society, is the preservation of their property; and the end why they choose and authorize a legislative, is, that there may be laws made, and rules set, as guards and fences to the properties of all the members of the society: to limit the power, and moderate the dominion, of every part and member of the society.”
—John Locke (1632–1704)
“Here [in London, history] ... seemed the very fabric of things, as if the city were a single growth of stone and brick, uncounted strata of message and meaning, age upon age, generated over the centuries to the dictates of some now all-but-unreadable DNA of commerce and empire.”
—William Gibson (b. 1948)