SNP Genotyping - Other Post-amplification Methods Based On Physical Properties of DNA

Other Post-amplification Methods Based On Physical Properties of DNA

The characteristic DNA properties of melting temperature and single stranded conformation have been used in several applications to distinguish SNP alleles. These methods very often achieve high specificity but require highly optimized conditions to obtain the best possible results.

Read more about this topic:  SNP Genotyping

Famous quotes containing the words methods, based, physical, properties and/or dna:

    The philosopher is in advance of his age even in the outward form of his life. He is not fed, sheltered, clothed, warmed, like his contemporaries. How can a man be a philosopher and not maintain his vital heat by better methods than other men?
    Henry David Thoreau (1817–1862)

    Captain, down where I come from we dearly love our whiskey, but we don’t drink with a man unless we respect him.
    James Poe, U.S. screenwriter, and Based On Play. Robert Aldrich. Sergeant Tolliver (Buddy Ebsen)

    ... the physical and domestic education of daughters should occupy the principal attention of mothers, in childhood: and the stimulation of the intellect should be very much reduced.
    Catherine E. Beecher (1800–1878)

    A drop of water has the properties of the sea, but cannot exhibit a storm. There is beauty of a concert, as well as of a flute; strength of a host, as well as of a hero.
    Ralph Waldo Emerson (1803–1882)

    Here [in London, history] ... seemed the very fabric of things, as if the city were a single growth of stone and brick, uncounted strata of message and meaning, age upon age, generated over the centuries to the dictates of some now all-but-unreadable DNA of commerce and empire.
    William Gibson (b. 1948)