Snake H/ACA box small nucleolar RNA refers to a number of very closely related non-coding RNA (ncRNA) genes identified in snakes which have been predicted to be small nucleolar RNAs (snoRNAs). This type of ncRNA is involved in the biogenesis of other small nuclear RNAs and are often referred to as 'guide' RNAs. They are usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
These snoRNA genes were initially identified in the introns of the cardiotoxin 4 and cobrotoxin genes of the Taiwan cobra (Bungarus multicinctus) and the Taiwan banded krait (Bungarus multicinctus) during sequencing of these genes. These snoRNAs are predicted to act as H/ACA box type methylation guides as they have the predicted hairpin-hinge-hairpin-tail structure and extended regions of complementarity to 5S ribosomal RNA (rRNA).
Famous quotes containing the words snake h, snake, box and/or small:
“If this creature is a murderer, then so are we all. This snake has killed one British soldier; we have killed many. This is not murder, gentlemen. This is war.”
—Administration in the State of Sout, U.S. public relief program (1935-1943)
“There’s a snake lurking in the grass.”
—Virgil [Publius Vergilius Maro] (70–19 B.C.)
“The quality of American life is an insult to the possibilities of human growth ... the pollution of American space, with gadgetry and cars and TV and box architecture, brutalizes the senses, making gray neurotics of most of us, and perverse spiritual athletes and strident self-transcenders of the best of us.”
—Susan Sontag (b. 1933)
“Much wondering to see upon all hands, of wattles and woodwork made,
Your bell-mounted churches, and guardless the sacred cairn and the rath,
And a small and a feeble populace stooping with mattock and spade,
Or weeding or ploughing with faces a-shining with much-toil wet;
While in this place and that place, with bodies unglorious, their chieftains stood....”
—William Butler Yeats (1865–1939)