Snake H/ACA box small nucleolar RNA refers to a number of very closely related non-coding RNA (ncRNA) genes identified in snakes which have been predicted to be small nucleolar RNAs (snoRNAs). This type of ncRNA is involved in the biogenesis of other small nuclear RNAs and are often referred to as 'guide' RNAs. They are usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
These snoRNA genes were initially identified in the introns of the cardiotoxin 4 and cobrotoxin genes of the Taiwan cobra (Bungarus multicinctus) and the Taiwan banded krait (Bungarus multicinctus) during sequencing of these genes. These snoRNAs are predicted to act as H/ACA box type methylation guides as they have the predicted hairpin-hinge-hairpin-tail structure and extended regions of complementarity to 5S ribosomal RNA (rRNA).
Famous quotes containing the words snake, box and/or small:
“If this creature is a murderer, then so are we all. This snake has killed one British soldier; we have killed many. This is not murder, gentlemen. This is war.”
—Administration in the State of Sout, U.S. public relief program (1935-1943)
“If you like to make things out of wood, or sew, or dance, or style people’s hair, or dream up stories and act them out, or play the trumpet, or jump rope, or whatever you really love to do, and you love that in front of your children, that’s going to be a far more important gift than anything you could ever give them wrapped up in a box with ribbons.”
—Fred M. Rogers (20th century)
“Westron wind, when will thou blow?
The small rain down can rain.
Christ, that my love were in my arms,
And I in my bed again.”
—Unknown. Western Wind (l. 1–4)