Snake H/ACA box small nucleolar RNA refers to a number of very closely related non-coding RNA (ncRNA) genes identified in snakes which have been predicted to be small nucleolar RNAs (snoRNAs). This type of ncRNA is involved in the biogenesis of other small nuclear RNAs and are often referred to as 'guide' RNAs. They are usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
These snoRNA genes were initially identified in the introns of the cardiotoxin 4 and cobrotoxin genes of the Taiwan cobra (Bungarus multicinctus) and the Taiwan banded krait (Bungarus multicinctus) during sequencing of these genes. These snoRNAs are predicted to act as H/ACA box type methylation guides as they have the predicted hairpin-hinge-hairpin-tail structure and extended regions of complementarity to 5S ribosomal RNA (rRNA).
Famous quotes containing the words snake, box and/or small:
“The Gospel of the army is cunning, as of all other human activities. The wisdom of the snake under the meekness of the sheep is what wins out.
The first Commandment is—never let them get anything on you—
The second: Graft—get privileges others haven’t got—worm yourself into confidence
The Third—seem neat and prosperous—as if you had money in the bank—”
—John Dos Passos (1896–1970)
“However low and poor the taking Snuff argues a Man to be in his own Stock of Thought, or Means to employ his Brains and his Fingers, yet there is a poorer Creature in the World than He, and this is a Borrower of Snuff; a Fellow that keeps no Box of his own, but is always asking others for a Pinch.”
—Richard Steele (1672–1729)
“Hail ye small sweet courtesies of life, for smooth do ye make the road of it! like grace and beauty which beget inclinations to love at first sight; ‘tis ye who open this door and let the stranger in.”
—Laurence Sterne (1713–1768)