Snake H/ACA box small nucleolar RNA refers to a number of very closely related non-coding RNA (ncRNA) genes identified in snakes which have been predicted to be small nucleolar RNAs (snoRNAs). This type of ncRNA is involved in the biogenesis of other small nuclear RNAs and are often referred to as 'guide' RNAs. They are usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
These snoRNA genes were initially identified in the introns of the cardiotoxin 4 and cobrotoxin genes of the Taiwan cobra (Bungarus multicinctus) and the Taiwan banded krait (Bungarus multicinctus) during sequencing of these genes. These snoRNAs are predicted to act as H/ACA box type methylation guides as they have the predicted hairpin-hinge-hairpin-tail structure and extended regions of complementarity to 5S ribosomal RNA (rRNA).
Famous quotes containing the words snake, box and/or small:
“Edible. Good to eat and wholesome to digest, as a worm to a toad, a toad to a snake, a snake to a pig, a pig to a man, and a man to a worm.”
—Ambrose Bierce (1842–1914)
“Such as boxed
Their feelings properly, complete to tags
A box for dark men and a box for Other
Would often find the contents had been scrambled.”
—Gwendolyn Brooks (b. 1917)
“They shall yet belie thy happy years
That say thou art a man. Diana’s lip
Is not more smooth and rubious; thy small pipe
Is as the maiden’s organ, shrill and sound,
And all is semblative a woman’s part.”
—William Shakespeare (1564–1616)