Snake H/ACA box small nucleolar RNA refers to a number of very closely related non-coding RNA (ncRNA) genes identified in snakes which have been predicted to be small nucleolar RNAs (snoRNAs). This type of ncRNA is involved in the biogenesis of other small nuclear RNAs and are often referred to as 'guide' RNAs. They are usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
These snoRNA genes were initially identified in the introns of the cardiotoxin 4 and cobrotoxin genes of the Taiwan cobra (Bungarus multicinctus) and the Taiwan banded krait (Bungarus multicinctus) during sequencing of these genes. These snoRNAs are predicted to act as H/ACA box type methylation guides as they have the predicted hairpin-hinge-hairpin-tail structure and extended regions of complementarity to 5S ribosomal RNA (rRNA).
Famous quotes containing the words snake h, snake, box and/or small:
“If this creature is a murderer, then so are we all. This snake has killed one British soldier; we have killed many. This is not murder, gentlemen. This is war.”
—Administration in the State of Sout, U.S. public relief program (1935-1943)
“The great snake lies ever half awake, at the bottom of the pit of the world, curled
In folds of himself until he awakens in hunger and moving his head to right and to left prepares for his hour to devour.”
—T.S. (Thomas Stearns)
“He holds the wire from this box of nerves
Praising the moral error
Of birth and death, the two sad knaves of thieves,
And the hunger’s emperor;
He pulls the chain, the cistern moves.”
—Dylan Thomas (1914–1953)
“Avarice, the spur of industry, is so obstinate a passion, and works its way through so many real dangers and difficulties, that it is not likely to be scared by an imaginary danger, which is so small that it scarcely admits of calculation.”
—David Hume (1711–1776)