Snake H/ACA box small nucleolar RNA refers to a number of very closely related non-coding RNA (ncRNA) genes identified in snakes which have been predicted to be small nucleolar RNAs (snoRNAs). This type of ncRNA is involved in the biogenesis of other small nuclear RNAs and are often referred to as 'guide' RNAs. They are usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
These snoRNA genes were initially identified in the introns of the cardiotoxin 4 and cobrotoxin genes of the Taiwan cobra (Bungarus multicinctus) and the Taiwan banded krait (Bungarus multicinctus) during sequencing of these genes. These snoRNAs are predicted to act as H/ACA box type methylation guides as they have the predicted hairpin-hinge-hairpin-tail structure and extended regions of complementarity to 5S ribosomal RNA (rRNA).
Famous quotes containing the words snake, box and/or small:
“The snake that cannot shed its skin perishes. Likewise those spirits who are prevented from changing their opinions; they cease to be spirits.”
—Friedrich Nietzsche (1844–1900)
“You’re the most beautiful woman I’ve ever painted. Not because you’re beautiful but because I’m in love with you. Hopelessly in love with you.”
—Muriel Box (b. 1905)
“Thirty-five years ago, when I was a college student, people wrote letters. The businessman who read, the lawyer who traveled; the dressmaker in evening school, my unhappy mother, our expectant neighbor: all conducted an often large and varied correspondence. It was the accustomed way of ordinarily educated people to occupy the world beyond their own small and immediate lives.”
—Vivian Gornick (b. 1935)