Snake H/ACA box small nucleolar RNA refers to a number of very closely related non-coding RNA (ncRNA) genes identified in snakes which have been predicted to be small nucleolar RNAs (snoRNAs). This type of ncRNA is involved in the biogenesis of other small nuclear RNAs and are often referred to as 'guide' RNAs. They are usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
These snoRNA genes were initially identified in the introns of the cardiotoxin 4 and cobrotoxin genes of the Taiwan cobra (Bungarus multicinctus) and the Taiwan banded krait (Bungarus multicinctus) during sequencing of these genes. These snoRNAs are predicted to act as H/ACA box type methylation guides as they have the predicted hairpin-hinge-hairpin-tail structure and extended regions of complementarity to 5S ribosomal RNA (rRNA).
Famous quotes containing the words snake, box and/or small:
“The great snake lies ever half awake, at the bottom of the pit of the world, curled
In folds of himself until he awakens in hunger and moving his head to right and to left prepares for his hour to devour.”
—T.S. (Thomas Stearns)
“A box of teak, a box of sandalwood,
A brass-ringed spyglass in a case,
A coin, leaf-thin with many polishings,
Last kingdom of a gold forgotten face,
These lie about the room....”
—Philip Larkin (1922–1986)
“What strikes me as odd now is how much my father managed to get across to me without those heart-to-hearts which I’ve read about fathers and sons having in the study or in the rowboat or in the car.... Somehow I understood completely how he expected me to behave, in small matters as well as large, even though I can’t remember being given any lectures about it beyond the occasional, undramatic “You might as well be a mensch.””
—Calvin Trillin (20th century)