Snake H/ACA box small nucleolar RNA refers to a number of very closely related non-coding RNA (ncRNA) genes identified in snakes which have been predicted to be small nucleolar RNAs (snoRNAs). This type of ncRNA is involved in the biogenesis of other small nuclear RNAs and are often referred to as 'guide' RNAs. They are usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
These snoRNA genes were initially identified in the introns of the cardiotoxin 4 and cobrotoxin genes of the Taiwan cobra (Bungarus multicinctus) and the Taiwan banded krait (Bungarus multicinctus) during sequencing of these genes. These snoRNAs are predicted to act as H/ACA box type methylation guides as they have the predicted hairpin-hinge-hairpin-tail structure and extended regions of complementarity to 5S ribosomal RNA (rRNA).
Famous quotes containing the words snake, box and/or small:
“There’s a snake lurking in the grass.”
—Virgil [Publius Vergilius Maro] (70–19 B.C.)
“A Cherokee is too smart to put anything in the contribution box of a race that’s robbed him of his birthright.”
—Howard Estabrook (1884–1978)
“Alice opened the door and found that it led into a small passage, not much larger than a rat hole: she knelt down and looked along the passage into the lovliest garden you ever saw. How she longed to get out of that dark hall, and wander about among those beds of bright flowers and those cool fountains, but she could not even get her head through the doorway.”
—Lewis Carroll [Charles Lutwidge Dodgson] (1832–1898)