Snake H/ACA box small nucleolar RNA refers to a number of very closely related non-coding RNA (ncRNA) genes identified in snakes which have been predicted to be small nucleolar RNAs (snoRNAs). This type of ncRNA is involved in the biogenesis of other small nuclear RNAs and are often referred to as 'guide' RNAs. They are usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
These snoRNA genes were initially identified in the introns of the cardiotoxin 4 and cobrotoxin genes of the Taiwan cobra (Bungarus multicinctus) and the Taiwan banded krait (Bungarus multicinctus) during sequencing of these genes. These snoRNAs are predicted to act as H/ACA box type methylation guides as they have the predicted hairpin-hinge-hairpin-tail structure and extended regions of complementarity to 5S ribosomal RNA (rRNA).
Famous quotes containing the words snake, box and/or small:
“Even in a bamboo tube, a snake still wants to wiggle.”
—Chinese proverb.
“I hate love. Hate being in love. I never want it to happen to me again.”
—Muriel Box (b. 1905)
“Poetry is the most direct and simple means of expressing oneself in words: the most primitive nations have poetry, but only quite well developed civilizations can produce good prose. So don’t think of poetry as a perverse and unnatural way of distorting ordinary prose statements: prose is a much less natural way of speaking than poetry is. If you listen to small children, and to the amount of chanting and singsong in their speech, you’ll see what I mean.”
—Northrop Frye (1912–1991)