Small nucleolar RNA R105/R108 refers to a group of related non-coding RNA (ncRNA) molecules which function in the biogenesis of other small nuclear RNAs (snRNAs). These small nucleolar RNAs (snoRNAs) are modifying RNAs and usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.
These two snoRNAs called R105 and R108 were identified in the plant Arabidopsis thaliana and are predicted to belong to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Famous quotes containing the word small:
“Alice opened the door and found that it led into a small passage, not much larger than a rat hole: she knelt down and looked along the passage into the lovliest garden you ever saw. How she longed to get out of that dark hall, and wander about among those beds of bright flowers and those cool fountains, but she could not even get her head through the doorway.”
—Lewis Carroll [Charles Lutwidge Dodgson] (1832–1898)