Small nucleolar RNA J33 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA J33 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. Plant snoRNA J33 was identified in a screen of Oryza sativa.
Famous quotes containing the word small:
“Seeing to it that a youngster grows up believing not just in the here and now but also in the grand maybes of life guarantees that some small yet crucial part of him remains forever a child.”
—Anne Cassidy (20th century)