Classes
There are three classes of SMAD:
- The receptor-regulated Smads (R-SMAD) which include SMAD1, SMAD2, SMAD3, SMAD5 and SMAD8/9
- The common-mediator Smad (co-SMAD) which includes only SMAD4, which interacts with R-SMADs to participate in signaling
- The antagonistic or inhibitory Smads (I-SMAD) which include SMAD6 and SMAD7, which block the activation of R-SMADs and Co-SMADs.
Read more about this topic: SMAD (protein)
Famous quotes containing the word classes:
“... too much attention is paid to dress by those who have neither the excuse of ample means nor of social claims.... The injury done by this state of things to the morals and the manners of our lower classes is incalculable.”
—Mrs. H. O. Ward (18241899)
“The want of education and moral training is the only real barrier that exists between the different classes of men. Nature, reason, and Christianity recognize no other. Pride may say Nay; but Pride was always a liar, and a great hater of the truth.”
—Susanna Moodie (18031885)
“Intellectuals can tell themselves anything, sell themselves any bill of goods, which is why they were so often patsies for the ruling classes in nineteenth-century France and England, or twentieth-century Russia and America.”
—Lillian Hellman (19071984)