SMAD (protein) - Classes

Classes

There are three classes of SMAD:

  1. The receptor-regulated Smads (R-SMAD) which include SMAD1, SMAD2, SMAD3, SMAD5 and SMAD8/9
  2. The common-mediator Smad (co-SMAD) which includes only SMAD4, which interacts with R-SMADs to participate in signaling
  3. The antagonistic or inhibitory Smads (I-SMAD) which include SMAD6 and SMAD7, which block the activation of R-SMADs and Co-SMADs.

Read more about this topic:  SMAD (protein)

Famous quotes containing the word classes:

    “The difference between people isn’t in their class, but in themselves. Only from the middle classes one gets ideas, and from the common people—life itself, warmth. You feel their hates and loves.”
    —D.H. (David Herbert)

    “There are three classes into which all the women past seventy that ever I knew were to be divided: 1. That dear old soul; 2. That old woman; 3. That old witch.”
    —Samuel Taylor Coleridge (1772–1834)

    “Genocide begins, however improbably, in the conviction that classes of biological distinction indisputably sanction social and political discrimination.”
    —Andrea Dworkin (b. 1946)