SLB may refer to:
- Schlumberger Limited New York Stock Exchange ticker symbol.
- Shard London Bridge, a skyscraper in London
- Sport Lisboa e Benfica, a Portuguese football (soccer) team.
- SLB Breakers Group, an online electrical store based in the United Kingdom.
- Sigma Lambda Beta International Fraternity, Inc., a Latino-based fraternity with multicultural membership.
- Sir Lord Baltimore, a pioneering heavy metal band.
- A Slide-Lid Box, a form of packaging for cigars, also known as a Cabinet box.
- Storm Lake Municipal Airport in Storm Lake, Iowa, United States
- Solomon Islands by the three letter ISO 3166-1 alpha-3 country code.
- Senior League Baseball
- Server Load Balancing, a concept in computer science.
- Sethu Lakshmi Bai higher secondary school in India
- Sanjay Leela Bhansali a highly acclaimed Indian film director, and his production company, SLB Films
- State Law Building, a high rise building in the CBD of Brisbane, Australia
- Superlambanana, a bright yellow fantasy sculpture located in Liverpool, England
- Simon Le Bon Lead singer, lyricist and musician of the band Duran Duran