Skin Flora - Relationship To Host

Relationship To Host

Skin microflora can be commensals, mutualistic or pathogens. Often they can be all three depending upon the strength of the person's immune system. Research upon the immune system in the gut and lungs has shown that microflora aids immunity development: however such research has only started upon whether this is the case with the skin. Pseudomonas aeruginosa is an example of a mutualistic bacterium that can turn into a pathogen and cause disease: if it gains entry into the blood system it can result in infections in bone, joint, gastrointestinal, and respiratory systems. It can also cause dermatitis. However, Pseudomonas aeruginosa produces antimicrobial substances such as pseudomonic acid (that are exploited commercially such as Mupirocin). This works against staphylococcal and streptococcal infections. Pseudomonas aeruginosa also produces substances that inhibit the growth of fungus species such as Candida krusei, Candida albicans, Torulopsis glabrata, Saccharomyces cerevisiae and Aspergillus fumigatus. It can also inhibit the growth of Helicobacter pylori. So important is its antimicrobial actions that it has been noted that "removing P. aeruginosa from the skin, through use of oral or topical antibiotics, may inversely allow for aberrant yeast colonization and infection."

Another aspect of bacteria is the generation of body odor. Sweat is odorless however several bacteria may consume it and create byproducts which may be considered putrid by man (as in contrast to flies, for example, that may find them attractive/appealing). Several examples are:

  • Propionibacteria in adolescent and adult sebaceous glands can turn its amino acids into propionic acid.
  • Staphylococcus epidermidis creates body odor by breaking sweat into isovaleric acid (3-methyl butanoic acid).
  • Bacillus subtilis creates strong foot odor.

Read more about this topic:  Skin Flora

Famous quotes containing the words relationship to, relationship and/or host:

    Sometimes in our relationship to another human being the proper balance of friendship is restored when we put a few grains of impropriety onto our own side of the scale.
    Friedrich Nietzsche (1844–1900)

    Every relationship that does not raise us up pulls us down, and vice versa; this is why men usually sink down somewhat when they take wives while women are usually somewhat raised up. Overly spiritual men require marriage every bit as much as they resist it as bitter medicine.
    Friedrich Nietzsche (1844–1900)

    Nothing is quite so wretchedly corrupt as an aristocracy which has lost its power but kept its wealth and which still has endless leisure to devote to nothing but banal enjoyments. All its great thoughts and passionate energy are things of the past, and nothing but a host of petty, gnawing vices now cling to it like worms to a corpse.
    Alexis de Tocqueville (1805–1859)