Species Distribution
Whereas bacteria and archaea encode either one or two sirtuins, eukaryotes encode several sirtuins in their genomes. In yeast, roundworms, and fruitflies, sir2 is the name of the sirtuin-type protein. This research started in 1991 by Leonard Guarente of MIT. Mammals possess seven sirtuins (SIRT1-7) that occupy different subcellular compartments such as the nucleus (SIRT1, -2, -6, -7), cytoplasm (SIRT1 and SIRT2) and the mitochondria (SIRT3, -4 and -5).
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Famous quotes containing the words species and/or distribution:
“The question that will decide our destiny is not whether we shall expand into space. It is: shall we be one species or a million? A million species will not exhaust the ecological niches that are awaiting the arrival of intelligence.”
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