Species Distribution
Whereas bacteria and archaea encode either one or two sirtuins, eukaryotes encode several sirtuins in their genomes. In yeast, roundworms, and fruitflies, sir2 is the name of the sirtuin-type protein. This research started in 1991 by Leonard Guarente of MIT. Mammals possess seven sirtuins (SIRT1-7) that occupy different subcellular compartments such as the nucleus (SIRT1, -2, -6, -7), cytoplasm (SIRT1 and SIRT2) and the mitochondria (SIRT3, -4 and -5).
Read more about this topic: Sirtuin
Famous quotes containing the words species and/or distribution:
“The French manner of hunting is gentlemanlike; ours is only for bumpkins and bodies. The poor beasts here are pursued and run down by much greater beasts than themselves; and the true British fox-hunter is most undoubtedly a species appropriated and peculiar to this country, which no other part of the globe produces.”
—Philip Dormer Stanhope, 4th Earl Chesterfield (1694–1773)
“My topic for Army reunions ... this summer: How to prepare for war in time of peace. Not by fortifications, by navies, or by standing armies. But by policies which will add to the happiness and the comfort of all our people and which will tend to the distribution of intelligence [and] wealth equally among all. Our strength is a contented and intelligent community.”
—Rutherford Birchard Hayes (1822–1893)