Species Distribution
Whereas bacteria and archaea encode either one or two sirtuins, eukaryotes encode several sirtuins in their genomes. In yeast, roundworms, and fruitflies, sir2 is the name of the sirtuin-type protein. This research started in 1991 by Leonard Guarente of MIT. Mammals possess seven sirtuins (SIRT1-7) that occupy different subcellular compartments such as the nucleus (SIRT1, -2, -6, -7), cytoplasm (SIRT1 and SIRT2) and the mitochondria (SIRT3, -4 and -5).
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Famous quotes containing the words species and/or distribution:
“Not only does every animal live at the expense of some other animal or plant, but the very plants are at war.... The individuals of a species are like the crew of a foundered ship, and none but good swimmers have a chance of reaching the land.”
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