Shimazu may refer to:
- Esther Shimazu (born 1957), an American/Hawaiian sculptor
- Saeko Shimazu (born 1959), a Japanese voice actor
- Shimazu clan, daimyō of the Satsuma han
- Shimazu Hisamitsu (1817-1887), a Japanese samurai prince
- Shimazu Katsuhisa (1503-1573), the fourteenth head of the Shimazu clan
- Shimazu Nariakira (1809-1858), a Japanese feudal lord (daimyō)
- Shimazu Tadahisa (died 1227), founder of the Shimazu clan
- Shimazu Tadatsune (1576-1638), a Tozama daimyo of Satsuma
- Shimazu Tadayoshi (1493-1568), a daimyō (feudal lord) of Satsuma
- Shimazu Takahisa (1514-1571), a daimyō during Japan's Sengoku period
- Shimazu Toshihisa (1537-1592), a senior retainer to the Shimazu clan
- Shimazu Yoshihiro (1535-1619), a general of the Shimazu clan
- Shimazu Yoshihisa (1533-1611), a daimyō of Satsuma
- Takako Shimazu (born 1939), a Japanese princess
- Yasujirō Shimazu (1897–1945), a Japanese film director