Target For Drugs
Shikimate can be used to synthesise (6S)-6-Fluoroshikimic acid, an antibiotic which inhibits the aromatic biosynthetic pathway.
Glyphosate, the active ingredient in the herbicide Roundup, kills plants by interfering with the shikimate pathway in plants. More specifically, glyphosate inhibits the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). "Roundup Ready" genetically modified crops overcome that inhibition.
Read more about this topic: Shikimic Acid
Famous quotes containing the words target and/or drugs:
“Well gentlemen, this is it. This is what we’ve been waiting for. Tonight your target is Tokyo. And you’re gonna play ‘em the Star Spangled Banner with two-ton bombs. All you’ve got to do is to remember what you’ve learned and follow your squadron leaders. They’ll get you in, and they’ll get you out. Any questions? All right that’s all. Good luck to you. Give ‘em hell.”
—Dudley Nichols (1895–1960)
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—C.E. (Charles Edward)