Shep may refer to:
- Shep (dog), a famous Blue Peter dog, a border collie, remembered by British TV viewers as inseparable from John Noakes
- Shep, a fictional character from the animated movie Interstella 5555: The 5tory of the 5ecret 5tar 5ystem
- Shep (American dog), a dog that lived in the Great Northern train station in Fort Benton, Montana, in the late 1930s
- Shep Messing, American soccer goalkeeper and current broadcaster
- Shep, George of the Jungle's elephant companion
- David Shepherd (umpire), English cricket umpire
- James Sheppard, lead singer of the Heartbeats and later Shep and the Limelites
- Jean Shepherd (born 1921) American raconteur, radio and TV personality, writer and actor