Role in Disease
Mutations may lead to decreased or increased activity of enzymes. This may have different consequences, depending on the normal function of the serine protease. For example, mutations in protein C, when leading to insufficient protein levels or activity, predispose to thrombosis.
Read more about this topic: Serine Protease
Famous quotes containing the words role in, role and/or disease:
“So successful has been the camera’s role in beautifying the world that photographs, rather than the world, have become the standard of the beautiful.”
—Susan Sontag (b. 1933)
“The role of the stepmother is the most difficult of all, because you can’t ever just be. You’re constantly being tested—by the children, the neighbors, your husband, the relatives, old friends who knew the children’s parents in their first marriage, and by yourself.”
—Anonymous Stepparent. Making It as a Stepparent, by Claire Berman, introduction (1980, repr. 1986)
“The artistic temperament is a disease that affects amateurs.... Artists of a large and wholesome vitality get rid of their art easily, as they breathe easily or perspire easily. But in artists of less force, the thing becomes a pressure, and produces a definite pain, which is called the artistic temperament.”
—Gilbert Keith Chesterton (1874–1936)