Serine Dehydratase - External Links

External Links

  • Serine dehydratase at the US National Library of Medicine Medical Subject Headings (MeSH)
Carbon-nitrogen lyases (EC 4.3)
4.3.1: ammonia-lyases
  • Histidine ammonia-lyase
  • Formiminotransferase cyclodeaminase
  • Serine dehydratase
4.3.2: amidine-lyases
  • Argininosuccinate lyase
  • Adenylosuccinate lyase
  • B
  • enzm
  • 1.1
    • 2
    • 3
    • 4
    • 5
    • 6
    • 7
    • 8
    • 10
    • 11
    • 13
    • 14
    • 15-18
  • 2.1
    • 2
    • 3
    • 4
    • 5
    • 6
    • 7
    • 8
  • 2.7.10
  • 2.7.11-12
  • 3.1
      • 3.1.3.48
    • 2
    • 3
    • 4
      • 3.4.21
    • 5
    • 6
    • 7
    • 22
    • 23
    • 24
  • 4.1
    • 2
    • 3
    • 4
    • 5
    • 6
  • 5.1
    • 2
    • 3
    • 4
    • 99
  • 6.1-3
    • 4
    • 5-6
Metabolism: amino acid metabolism · synthesis and catabolism enzymes (essential in CAPS)
K→acetyl-CoA
LYSINE→
  • Saccharopine dehydrogenase
  • Glutaryl-CoA dehydrogenase
LEUCINE→
  • Branched chain aminotransferase
  • Branched-chain alpha-keto acid dehydrogenase complex
  • Isovaleryl coenzyme A dehydrogenase
  • Methylcrotonyl-CoA carboxylase
  • Methylglutaconyl-CoA hydratase
  • 3-hydroxy-3-methylglutaryl-CoA lyase
TRYPTOPHAN→
  • Indoleamine 2,3-dioxygenase/Tryptophan 2,3-dioxygenase
  • Arylformamidase
  • Kynureninase
  • 3-hydroxyanthranilate oxidase
  • Aminocarboxymuconate-semialdehyde decarboxylase
  • Aminomuconate-semialdehyde dehydrogenase
PHENYLALANINE→tyrosine→ (see below)
G
G→pyruvate
→citrate
glycine→serine→
  • Serine hydroxymethyltransferase
  • Serine dehydratase
  • glycine→creatine: Guanidinoacetate N-methyltransferase
  • Creatine kinase
alanine→
  • Alanine transaminase
cysteine→
  • D-cysteine desulfhydrase
threonine→
  • L-threonine dehydrogenase
G→glutamate→
α-ketoglutarate
HISTIDINE→
  • Histidine ammonia-lyase
  • Urocanate hydratase
  • Formiminotransferase cyclodeaminase
proline→
  • Proline oxidase
  • Pyrroline-5-carboxylate reductase
  • 1-Pyrroline-5-carboxylate dehydrogenase/ALDH4A1
  • PYCR1
arginine→
  • Ornithine aminotransferase
  • Ornithine decarboxylase
  • Agmatinase
→alpha-ketoglutarate→TCA
  • Glutamate dehydrogenase
Other
  • cysteine+glutamate→glutathione: Gamma-glutamylcysteine synthetase
  • Glutathione synthetase
  • Gamma-glutamyl transpeptidase
  • glutamate→glutamine: Glutamine synthetase
  • Glutaminase
G→propionyl-CoA→
succinyl-CoA
VALINE→
  • Branched chain aminotransferase
  • Branched-chain alpha-keto acid dehydrogenase complex
  • Enoyl-CoA hydratase
  • 3-hydroxyisobutyryl-CoA hydrolase
  • 3-hydroxyisobutyrate dehydrogenase
  • Methylmalonate semialdehyde dehydrogenase
ISOLEUCINE→
  • Branched chain aminotransferase
  • Branched-chain alpha-keto acid dehydrogenase complex
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
METHIONINE→
  • generation of homocysteine: Methionine adenosyltransferase
  • Adenosylhomocysteinase
  • regeneration of methionine: Methionine synthase/Homocysteine methyltransferase
  • Betaine-homocysteine methyltransferase
  • conversion to cysteine: Cystathionine beta synthase
  • Cystathionine gamma-lyase
THREONINE→
  • Threonine aldolase
→succinyl-CoA→TCA
  • Propionyl-CoA carboxylase
  • Methylmalonyl CoA epimerase
  • Methylmalonyl-CoA mutase
G→fumarate
PHENYLALANINE→tyrosine→
  • Phenylalanine hydroxylase
  • Tyrosine aminotransferase
  • 4-Hydroxyphenylpyruvate dioxygenase
  • Homogentisate 1,2-dioxygenase
  • Fumarylacetoacetate hydrolase
  • tyrosine→melanin: Tyrosinase
G→oxaloacetate
asparagine→aspartate→
  • Asparaginase/Asparagine synthetase
  • Aspartate transaminase

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

Read more about this topic:  Serine Dehydratase

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