Bias
The statistics of a trial that is stopped early at only n samples are different than a similar trial that is run for a predetermined number of trials, even if they end up collecting the same number of samples. If this is not accounted for when interpreting the sequential trial, the results will be biased. Therefore it is important that proper methodology is followed in order to avoid false conclusions. See for a discussion.
Read more about this topic: Sequential Analysis
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—Ralph Waldo Emerson (1803–1882)