Threats To The Plan
The plan came close to failure in Foundation and Empire because of the mutant called The Mule. Because the Mule had psychic powers of mind control, he did not fit the model of interactions psychohistory was based upon. The Mule could influence men at a distance, unlike Second Foundation agents, who required eye contact. The Mule was eventually lured to a remote planet to destroy the Second Foundation. However, in so doing, he left his main fleet, which was turned against him by Second Foundation agents in his absence, thus ending his rule.
Read more about this topic: Seldon Plan
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