Immunoreactivity
The different classes of Schwann cells express characteristic antigenic markers that can be targeted with antibodies. Myelinating Schwann cells can be visualised by immunohistochemistry using antibodies against the proteins S-100, Myelin protein zero (P-Zero) and Myelin basic protein (MBP). Non-myelinating Schwann cells such as those that form Remak bundles and terminal Schwann cells are positive for S-100 and Glial fibrillary acidic protein (GFAP).
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