Schistosoma Japonicum - Treatment

Treatment

The chemotherapy of choice is praziquantel, a quinolone derivative. Praziquantel is generally administered in an oral form in one or two doses from 40–60 mg/kg body weight.

Combination treatment may prevent morbidity due to schistosomiasis. Praziquantel is most active against adult worms. However, it has been found that artemether prevents the development of adult worms, thus decreasing egg production in the host. If both praziquantel and artemether can be used together, the entire lifespan of S. japonicum would be covered in the vertebrate host.

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