Sarcosine Dehydrogenase - Structure

Structure

There is no crystal structure available for sarcosine dehydrogenase. Sarcosine dehydrogenase contains a covalently bound FAD group " linked via the 8 alpha position of the isoalloxazine ring to an imidazole N(3) of a histidine residue". The enzyme, according to Freisell Wr. et al., also contains non-heme iron in a ratio of 1 or 2 iron per 300000g of enzyme, and 0.5 mol of acid soluble sulfur suggesting that the electron transfer during the first step in the reaction might proceed through a different pathway than that of Fe-S clusters.

Read more about this topic:  Sarcosine Dehydrogenase

Famous quotes containing the word structure:

    “A structure becomes architectural, and not sculptural, when its elements no longer have their justification in nature.”
    —Guillaume Apollinaire (1880–1918)

    “Who says that fictions only and false hair
    Become a verse? Is there in truth no beauty?
    Is all good structure in a winding stair?
    May no lines pass, except they do their duty
    Not to a true, but painted chair?”
    —George Herbert (1593–1633)

    “... the structure of a page of good prose is, analyzed logically, not something frozen but the vibrating of a bridge, which changes with every step one takes on it.”
    —Robert Musil (1880–1942)