Sarcosine Dehydrogenase - Structure

Structure

There is no crystal structure available for sarcosine dehydrogenase. Sarcosine dehydrogenase contains a covalently bound FAD group " linked via the 8 alpha position of the isoalloxazine ring to an imidazole N(3) of a histidine residue". The enzyme, according to Freisell Wr. et al., also contains non-heme iron in a ratio of 1 or 2 iron per 300000g of enzyme, and 0.5 mol of acid soluble sulfur suggesting that the electron transfer during the first step in the reaction might proceed through a different pathway than that of Fe-S clusters.

Read more about this topic:  Sarcosine Dehydrogenase

Famous quotes containing the word structure:

    I really do inhabit a system in which words are capable of shaking the entire structure of government, where words can prove mightier than ten military divisions.
    Václav Havel (b. 1936)

    Vashtar: So it’s finished. A structure to house one man and the greatest treasure of all time.
    Senta: And a structure that will last for all time.
    Vashtar: Only history will tell that.
    Senta: Sire, will he not be remembered?
    Vashtar: Yes, he’ll be remembered. The pyramid’ll keep his memory alive. In that he built better than he knew.
    William Faulkner (1897–1962)

    The question is still asked of women: “How do you propose to answer the need for child care?” That is an obvious attempt to structure conflict in the old terms. The questions are rather: “If we as a human community want children, how does the total society propose to provide for them?”
    Jean Baker Miller (20th century)