Sarcosine Dehydrogenase - Structure

Structure

There is no crystal structure available for sarcosine dehydrogenase. Sarcosine dehydrogenase contains a covalently bound FAD group " linked via the 8 alpha position of the isoalloxazine ring to an imidazole N(3) of a histidine residue". The enzyme, according to Freisell Wr. et al., also contains non-heme iron in a ratio of 1 or 2 iron per 300000g of enzyme, and 0.5 mol of acid soluble sulfur suggesting that the electron transfer during the first step in the reaction might proceed through a different pathway than that of Fe-S clusters.

Read more about this topic:  Sarcosine Dehydrogenase

Famous quotes containing the word structure:

    In the extent and proper structure of the Union, therefore, we behold a republican remedy for the diseases most incident to republican government.
    James Madison (1751–1836)

    The question is still asked of women: “How do you propose to answer the need for child care?” That is an obvious attempt to structure conflict in the old terms. The questions are rather: “If we as a human community want children, how does the total society propose to provide for them?”
    Jean Baker Miller (20th century)

    With sixty staring me in the face, I have developed inflammation of the sentence structure and definite hardening of the paragraphs.
    James Thurber (1894–1961)