Sanitarium may refer to:
- An alternate spelling of sanatorium, which may refer to a medical facility for long-term illness, or a health-oriented resort, depending on region
- Sanitarium, California, in Napa County
- Battle Creek Sanitarium, made famous by John Harvey Kellogg
- Sanitarium Health Food Company, a major food company in Australia and New Zealand
- Sanitarium (video game), a point-and-click adventure game released in 1998
- "Welcome Home (Sanitarium)," a song by Metallica
- The Sanitarium, a 1910 film starring Fatty Arbuckle