Sanford-Burnham Medical Research Institute - Select Scientific Achievements

Select Scientific Achievements

  • 1971: Eva Engvall, one of the scientists who invented ELISA in 1971, worked at Sanford-Burnham. She continues to serve as an Adjunct Professor.
  • 1984: Discovered cell adhesion regulator RGD (Erkki Ruoslahti, M.D., Ph.D.)
  • 1988: Collaborative discovery of the role TGF beta plays in tissue scarring. Based on this research, two clinical trials are underway: one for the treatment of pulmonary fibrosis and another for the treatment of renal cell carcinoma and melanoma (Erkki Ruoslahti, M.D., Ph.D.)
  • 1992: Observed that the activity of common anti-cancer drugs requires “cell suicide” of the cancer cells (apoptosis) and subsequently discovered novel proteins important in apoptosis (John C. Reed, M.D., Ph.D.)
  • 1997: Discovered peptides that home to specific organs. These peptides were later used as targeting elements to deliver nanoparticles into tumors and other sites of disease (Erkki Ruoshlahti, M.D., Ph.D.)
  • 2001: Solved the 3-dimensional structure of the anthrax toxin, leading to the creation of the world’s most potent chemical inhibitor of anthrax (Robert Liddington, Ph.D.)
  • 2009: Solved the crystal structure of the influenza hemagglutinin (H5) in complex with a broad spectrum neutralizing antibody (Robert Liddington, Ph.D.)

Read more about this topic:  Sanford-Burnham Medical Research Institute

Famous quotes containing the words select, scientific and/or achievements:

    Why does he not know how to select servants? The ordinary procedure of the nineteenth century is that when a powerful and noble personage encounters a man of feeling, he kills, exiles, imprisons or so humiliates him that the other, like a fool, dies of grief.
    Stendhal [Marie Henri Beyle] (1783–1842)

    The scientific mind does not so much provide the right answers as ask the right questions.
    Claude Lévi-Strauss (b. 1908)

    Our achievements speak for themselves. What we have to keep track of are our failures, discouragements, and doubts. We tend to forget the past difficulties, the many false starts, and the painful groping. We see our past achievements as the end result of a clean forward thrust, and our present difficulties as signs of decline and decay.
    Eric Hoffer (1902–1983)