Select Scientific Achievements
- 1971: Eva Engvall, one of the scientists who invented ELISA in 1971, worked at Sanford-Burnham. She continues to serve as an Adjunct Professor.
- 1984: Discovered cell adhesion regulator RGD (Erkki Ruoslahti, M.D., Ph.D.)
- 1988: Collaborative discovery of the role TGF beta plays in tissue scarring. Based on this research, two clinical trials are underway: one for the treatment of pulmonary fibrosis and another for the treatment of renal cell carcinoma and melanoma (Erkki Ruoslahti, M.D., Ph.D.)
- 1992: Observed that the activity of common anti-cancer drugs requires “cell suicide” of the cancer cells (apoptosis) and subsequently discovered novel proteins important in apoptosis (John C. Reed, M.D., Ph.D.)
- 1997: Discovered peptides that home to specific organs. These peptides were later used as targeting elements to deliver nanoparticles into tumors and other sites of disease (Erkki Ruoshlahti, M.D., Ph.D.)
- 2001: Solved the 3-dimensional structure of the anthrax toxin, leading to the creation of the world’s most potent chemical inhibitor of anthrax (Robert Liddington, Ph.D.)
- 2009: Solved the crystal structure of the influenza hemagglutinin (H5) in complex with a broad spectrum neutralizing antibody (Robert Liddington, Ph.D.)
Read more about this topic: Sanford-Burnham Medical Research Institute
Famous quotes containing the words select, scientific and/or achievements:
“Here lies the body of Sir John Guise.
Nobody laughs, and nobody cries;
Where his soul is and how it fares
Nobody knows and nobody cares.”
—Anonymous. From Frobisher’s New Select Collection of Epitaphs (c. 1791)
“We have our little theory on all human and divine things. Poetry, the workings of genius itself, which, in all times, with one or another meaning, has been called Inspiration, and held to be mysterious and inscrutable, is no longer without its scientific exposition. The building of the lofty rhyme is like any other masonry or bricklaying: we have theories of its rise, height, decline and fall—which latter, it would seem, is now near, among all people.”
—Thomas Carlyle (1795–1881)
“Our achievements speak for themselves. What we have to keep track of are our failures, discouragements, and doubts. We tend to forget the past difficulties, the many false starts, and the painful groping. We see our past achievements as the end result of a clean forward thrust, and our present difficulties as signs of decline and decay.”
—Eric Hoffer (1902–1983)