Select Scientific Achievements
- 1971: Eva Engvall, one of the scientists who invented ELISA in 1971, worked at Sanford-Burnham. She continues to serve as an Adjunct Professor.
- 1984: Discovered cell adhesion regulator RGD (Erkki Ruoslahti, M.D., Ph.D.)
- 1988: Collaborative discovery of the role TGF beta plays in tissue scarring. Based on this research, two clinical trials are underway: one for the treatment of pulmonary fibrosis and another for the treatment of renal cell carcinoma and melanoma (Erkki Ruoslahti, M.D., Ph.D.)
- 1992: Observed that the activity of common anti-cancer drugs requires “cell suicide” of the cancer cells (apoptosis) and subsequently discovered novel proteins important in apoptosis (John C. Reed, M.D., Ph.D.)
- 1997: Discovered peptides that home to specific organs. These peptides were later used as targeting elements to deliver nanoparticles into tumors and other sites of disease (Erkki Ruoshlahti, M.D., Ph.D.)
- 2001: Solved the 3-dimensional structure of the anthrax toxin, leading to the creation of the world’s most potent chemical inhibitor of anthrax (Robert Liddington, Ph.D.)
- 2009: Solved the crystal structure of the influenza hemagglutinin (H5) in complex with a broad spectrum neutralizing antibody (Robert Liddington, Ph.D.)
Read more about this topic: Sanford-Burnham Medical Research Institute
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“We select granite for the underpinning of our houses and barns; we build fences of stone; but we do not ourselves rest on an underpinning of granitic truth, the lowest primitive rock. Our sills are rotten.”
—Henry David Thoreau (18171862)
“A nap, my friend, is a brief period of sleep which overtakes superannuated persons when they endeavour to entertain unwelcome visitors or to listen to scientific lectures.”
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“When science, art, literature, and philosophy are simply the manifestation of personality, they are on a level where glorious and dazzling achievements are possible, which can make a mans name live for thousands of years. But above this level, far above, separated by an abyss, is the level where the highest things are achieved. These things are essentially anonymous.”
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