Post-retirement
De retired in 1973 from the Calcutta Medical College at the age of 58. After his retirement, he showed no interest in higher positions but continued his research at the Bose Institute, Calcutta. De’s desire to purify the cholera toxin did not progress any further as the protein purification technology was not well established in his research settings. During his time of research, De worked with hypertoxin-producing classical strains of V. cholerae O1, which was abruptly replaced by El Tor biotype in Calcutta from 1963. This new development was another reason why De could not continue his research on purification of cholera toxin.
In 1978, the Nobel Foundation invited De to participate in the 43rd Nobel Symposium on Cholera and Related Diarrhoeas.
De died on April 15, 1985 at the age of 70. His life’s ambition was to make the world a better place to live in through his dedicated selfless services in medical science.
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