Tissue Distribution
In humans, Robo1 is expressed generally throughout the central nervous system. Robo2 is enriched in most regions of the adult and fetal brain, as well as in the adult ovary. Intermediate expression of Robo2 is seen in the fetal liver and adult lung, kidney, spleen, testes, and spinal cord. Robo3/Rig1 is found in the hindbrain and spinal cord. Robo4 is expressed in the heart, liver, lungs, kidney, muscle, small intestine, endothelial cells, and largely in the placenta.
Read more about this topic: Roundabout (gene)
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