Glioma Invasion and Migration Inhibition
Robo1 is thought to play a role in the inhibition of glioma invasion and migration. Glioblastoma cells grow away from areas that contain high concentrations of Slit2 and its receptor Robo1, suggesting that the Robo1/Slit2 complex can serve as a chemorepellent for glioma cells, inhibiting the invasion and migration of the tumor cells.
Read more about this topic: Roundabout (gene), Function
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—William Howard Taft (1857–1930)