Glioma Invasion and Migration Inhibition
Robo1 is thought to play a role in the inhibition of glioma invasion and migration. Glioblastoma cells grow away from areas that contain high concentrations of Slit2 and its receptor Robo1, suggesting that the Robo1/Slit2 complex can serve as a chemorepellent for glioma cells, inhibiting the invasion and migration of the tumor cells.
Read more about this topic: Roundabout (gene), Function
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“In our governments the real power lies in the majority of the community, and the invasion of private rights is chiefly to be apprehended, not from the acts of government contrary to the sense of the constituents, but from the acts in which government is the mere instrument of the majority.”
—James Madison (1751–1836)