Rostral Migratory Stream - Brief History

Brief History

The RMS was named and discovered by J. Altman in 1969 using 3H-thymidine autoradiography in the rat brain. He traced the migration of labeled cells from the SVZ, which is situated throughout the lateral walls of the lateral ventricles, rostrally to the main olfactory bulb. He also quantitatively studied the effect of age on the size of the RMS. There is still some ongoing debate about the extent of the RMS and adult SVZ neurogenesis of new neurons in humans.

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