Rosanna may refer to:
- Rosanna (given name)
- "Rosanna" (song), a song by Toto
- Rosanna shuffle, the drum pattern from the song
- Rosanna (film), a 1953 Mexican film
- Rosanna (Transformers), a fictional character
- Rosanna, Victoria, a suburb of Melbourne
- Rosanna railway station
- Rosanna, a community in the township of Norwich, Ontario, Canada
- Rosanna, a river tributary to the Sanna in Austria