RNA Editing - RNA Editing May Be Involved in RNA Degradation

RNA Editing May Be Involved in RNA Degradation

A recent study looked at the involvement of RNA editing in RNA degradation. The researchers specifically looked at the interaction between ADAR1 and hUpf1, an enzyme involved in the nonsense-mediated mRNA decay pathway(NMD). They found that ADAR1 and hUpf1 are found within the suprasliceosome and they form a complex that leads to the down-regulation of specific genes. The exact mechanism or the exact pathways that these two are involved in are unknown at this time. The only fact that this research has shown is that they form a complex and down-regulate specific genes.

Read more about this topic:  RNA Editing

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