Role in Embryonic Development
RNA-binding proteins’ transcriptional and post-transcriptional regulation of RNA has a role in regulating the patterns of gene expression during development. Extensive research on the nematode C. elegans has identified RNA-binding proteins as essential factors during germline and early embryonic development. Their specific function involves the development of somatic tissues (neurons, hypodermis, muscles and excretory cells) as well as providing timing cues for the developmental events. Nevertheless, it is exceptionally challenging to discover the mechanism behind RBPs' function in development due to the difficulty in identifying their RNA targets. This is because most RBPs usually have multiple RNA targets. However, it is indisputable that RBPs exert a critical control in regulating developmental pathways in a concerted manner.
Read more about this topic: RNA-binding Protein
Famous quotes containing the words role, embryonic and/or development:
“His role was as the gentle teacher, the logical, compassionate, caring and articulate teacher, who inspired you so that you wanted to please him more than life itself.”
—Carol Lawrence, U.S. singer, star of West Side Story. Conversations About Bernstein, p. 172, ed. William Westbrook Burton, Oxford University Press (1995)
“Quintilian [educational writer in Rome around A.D. 100] thought that the earliest years of the child’s life were crucial. Education should start earlier than age seven, within the family. It should not be so hard as to give the child an aversion to learning. Rather, these early lessons would take the form of play—that embryonic notion of kindergarten.”
—C. John Sommerville (20th century)
“A defective voice will always preclude an artist from achieving the complete development of his art, however intelligent he may be.... The voice is an instrument which the artist must learn to use with suppleness and sureness, as if it were a limb.”
—Sarah Bernhardt (1845–1923)