Diversity
As nuclear RNA emerges from RNA polymerase, RNA transcripts are immediately covered with RNA-binding proteins that regulate every aspect of RNA metabolism and function including RNA biogenesis, maturation, transport, cellular localization and stability. All RBPs bind RNA, however they do so with different RNA-sequence specificities and affinities, which allows the RBPs to be as diverse as their targets and functions. These targets include mRNA, which codes for proteins, as well as a number of functional non-coding RNAs. NcRNAs almost always function as ribonucleoprotein complexes and not as naked RNAs. These non-coding RNAs include microRNAs, small interfering RNAs (siRNA), as well as splicesomal small nuclear RNAs (snRNA).
Read more about this topic: RNA-binding Protein
Famous quotes containing the word diversity:
“The diversity in the faculties of men, from which the rights of property originate, is not less an insuperable obstacle to a uniformity of interests. The protection of these faculties is the first object of government.”
—James Madison (1751–1836)
“We call the intention good which is right in itself, but the action is good, not because it contains within it some good, but because it issues from a good intention. The same act may be done by the same man at different times. According to the diversity of his intention, however, this act may be at one time good, at another bad.”
—Peter Abelard (1079–1142)
“What we have to do ... is to find a way to celebrate our diversity and debate our differences without fracturing our communities.”
—Hillary Rodham Clinton (b. 1947)