Function
Recent evidence suggests RRF may accomplish the recycling of ribosomes by splitting ribosomes into subunits, thereby releasing the bound mRNA.
Loss of RRF Function:
- In Bacteria (specifically Escherichia coli), loss of the gene encoding RRF is deleterious. This makes RRF a possible target for new antibacterial drugs.
- Yeast mitochondrial RRF (mtRRF) is encoded by a gene in the cell nucleus. Loss of function of this gene leads to mitochondrial genome instability and respiratory incompetence.
Read more about this topic: Ribosome Recycling Factor
Famous quotes containing the word function:
“The function of the actor is to make the audience imagine for the moment that real things are happening to real people.”
—George Bernard Shaw (1856–1950)
“The intension of a proposition comprises whatever the proposition entails: and it includes nothing else.... The connotation or intension of a function comprises all that attribution of this predicate to anything entails as also predicable to that thing.”
—Clarence Lewis (1883–1964)
“To look backward for a while is to refresh the eye, to restore it, and to render it the more fit for its prime function of looking forward.”
—Margaret Fairless Barber (1869–1901)