Function
Recent evidence suggests RRF may accomplish the recycling of ribosomes by splitting ribosomes into subunits, thereby releasing the bound mRNA.
Loss of RRF Function:
- In Bacteria (specifically Escherichia coli), loss of the gene encoding RRF is deleterious. This makes RRF a possible target for new antibacterial drugs.
- Yeast mitochondrial RRF (mtRRF) is encoded by a gene in the cell nucleus. Loss of function of this gene leads to mitochondrial genome instability and respiratory incompetence.
Read more about this topic: Ribosome Recycling Factor
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