Presentation
The syndrome is characterized by dyspnea, fever, weight gain, hypotension, and pulmonary infiltrates. This is effectively treated by giving dexamethasone and holding ATRA (or arsenic trioxide) in severe cases. An elevated white count is sometimes associated with this syndrome, but is not a prerequisite.
Once RAS has resolved, pro-differentiation chemotherapy can be resumed.
Read more about this topic: Retinoic Acid Syndrome
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