Reston Virus - History and Current Knowledge

History and Current Knowledge

RESTV was discovered in crab-eating macaques from Hazleton Laboratories (now Covance) in 1989. This attracted significant media attention due to the proximity of Reston to the Washington, DC metro area, and the lethality of a closely related virus, Ebola virus (EBOV). Despite its status as a level-4 organism, Reston virus is non-pathogenic to humans however hazardous to monkeys; the perception of its lethality was confounded due to the monkey's coinfection with Simian hemorrhagic fever virus (SHFV).

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