The term resistance mutation is most commonly used to describe point mutations in virus genes that allow the virus to become resistant to treatment with a particular antiviral drug. The term is now being seen with more frequency in bacteriology and parasitology. The term "resistance mutation" first appeared in the management of HIV, which was the first virus in which genome sequencing is routinely used to look for drug resistance.
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Famous quotes containing the word resistance:
“The greatest, or rather the most prominent, part of this city was constructed with the design to offer the deadest resistance to leaden and iron missiles that might be cast against it. But it is a remarkable meteorological and psychological fact, that it is rarely known to rain lead with much violence, except on places so constructed.”
—Henry David Thoreau (1817–1862)