Cast
- Milla Jovovich as Alice; a former Umbrella Corporation security officer whose exposure to the T-Virus granted her superhuman abilities.
- Ali Larter as Claire Redfield; Chris' younger sister who led a convoy of survivors who encountered Alice in the previous film.
- Wentworth Miller as Chris Redfield; Claire's older brother who is working with an unnamed military organization combating the infected.
- Boris Kodjoe as Luther West; a former professional basketball player and the leader of the survivors of Los Angeles.
- Kim Coates as Bennett Sinclair; a film producer and one of the survivors of Los Angeles
- Shawn Roberts as Albert Wesker; the Chairman of the Umbrella Corporation who possesses superhuman strength, speed, and regenerative capabilities.
- Spencer Locke as K-Mart; a young girl named after the department store where she was discovered hiding, and a member of Claire's convoy of survivors in the previous film.
- Kacey Barnfield as Crystal Waters; a junior champ in swimming in her high school days, she came to Los Angeles to work as an actress and is one of the survivors.
- Norman Yeung as Kim Yong; Bennett's former intern before the virus outbreak.
- Sergio Peris-Mencheta as Angel Ortiz, a survivor in Los Angeles.
- Sienna Guillory as Jill Valentine; a former S.T.A.R.S. operative who assisted Alice and escaped Raccoon City in Resident Evil: Apocalypse.
- Mika Nakashima as J-Pop Girl; the first infected person in Tokyo from the opening scene who attacks a man.
- Ray Olubowale as the Axeman; a monster taken from the game Resident Evil 5 (known as The Executioner).
Read more about this topic: Resident Evil: Afterlife
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—Charlotte Brontë (1816–1855)