Overview Table
| Characteristic | proximal tubule | loop of Henle | Distal convoluted tubule | Collecting duct system | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| S1 | S2 | S3 | descending limb | thin ascending limb | thick ascending limb | connecting tubule | initial collecting tubule | cortical collecting ducts | medullary collecting ducts | ||
| reabsorption (%) | 67% | 25% | 5% | 3% | |||||||
| reabsorption (mmoles/day) | ~17,000 | ~6,400 | ~1,300 | ~700 | |||||||
| Concentration (mM) | 142 | 142 | 100 | 70 | 40 | ||||||
| electrical driving force (mV) | -3 | +3 | +15 | -5 to +5 | -40 | ||||||
| chemical driving force (mV) | 0 | 0 | -9 | -19 | -34 | ||||||
| electrochemical driving force (mV) | -3 | +3 | +6 | -24 to -14 | -74 | ||||||
| apical transport proteins | SGLT, Na-H antiporter | (passively) | Na-K-2Cl symporter (Na-H antiporter and passively) |
sodium-chloride symporter | ENaC | ||||||
| basolateral transport proteins | Na+/K+-ATPase | ||||||||||
| Other reabsorption features | isosmotic | by principal cells, stimulated by aldosterone | |||||||||
Read more about this topic: Renal Sodium Reabsorption
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