Reissner's membrane (vestibular membrane, vestibular wall) is a membrane inside the cochlea of the inner ear. It separates scala media from scala vestibuli. Together with the basilar membrane it creates a compartment in the cochlea filled with endolymph, which is important for the function of the organ of Corti. It primarily functions as a diffusion barrier, allowing nutrients to travel from the perilymph to the endolymph of the membranous labyrinth.
Histologically, the membrane is composed of two layers of flattened epithelium, separated by a basal lamina. Its structure suggests that its function is transport of fluid and electrolytes.
Reissner's membrane is named after German anatomist Ernst Reissner (1824-1878).
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