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- Redhook Ale Brewery, a brewery which produces the Redhook brand of beer
- The Horror at Red Hook, a short story by H. P. Lovecraft, set in Red Hook, Brooklyn
- Red Hook (FBI), a surveillance tool developed by the Federal Bureau of Investigation
- Red Hook (novel), by Reggie Nadelson
- Red Hook (novel), by Gabriel Cohen
- Red Hook (film), a 2009 film by Elizabeth Lucas
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