Receptor (biochemistry) - Receptor Regulation

Receptor Regulation

Cells can increase (upregulate) or decrease (downregulate) the number of receptors to a given hormone or neurotransmitter to alter its sensitivity to this molecule. This is a locally acting feedback mechanism.

  • Receptor desensitization
  • Uncoupling of receptor effector molecules.
  • Receptor sequestration (internalization).

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